apoB measurement is a better risk-gauger (than total cholesterol)
So to gauge the true extent of your [cardivascular] risk, we have to know how many of these apoB particles are circulating in your bloodstream. That number is much more relevant than the total quantity of cholesterol that these particles are carrying. - Outlive see Atherosclerosis
Amount of cholesterol >2-fold per apoB particle.
- LDL is wrapped by 1-apoB particle.
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the amount of cholesterol per LDL particle varies >2-fold between individuals - pmc.nih.gov
- Hence, the amount of cholesterol per apoB particle varries >2-fold. And each separate apoB particle presents risk, not total cholesterol. Therefore we should measure apoB not just LDL/HDL.
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